Acr contrast manual sickle cell

Policy and Procedure Manual. Per the ACR guidelines, there is no agreed-upon threshold of serum creatinine elevation or eGFR Patients with Sickle-Cell may receive contrast medium. Myasthenia Gravis: There is a questionable relationship between IV iodinated contrast. to the American College of Radiology’s Manual on Contrast Media (v. 7) (9). In a recently added section, the authors of this document state ‘‘ it is our opinion that any special risk to sickle cell patients from IV administered GBCM at currently approved dosages. This manual was developed by the ACR Committee on Drugs and Contrast Media of the ACR Commission on Quality and Safety as a guide for radiologists to enhance the safe and effective use of contrast media.

Sickle cell disease: There has been a theoretical concern that GBCA may potentiate magnetic alignment of sickle cells and result in a vaso-occlusive crisis. However, no studies have supported this claim. Therefore, ACR does not recommend withholding either GBCA or ICM in patients with sickle cell disease [6]. Background: Increased sickling of erythrocytes following intravenous iodinated contrast has been described in patients with sickle cell disease. In vitro, the effect is correlated with the tonicity, viscosity, acidity, and ionic nature of contrast media. Less erythrocyte sickling is observed in vitro with second-generation low- and iso-osmolar contrast agents. Sickle cell disease is associated with an increased risk of ischemic stroke in children. TCD has been shown to be extremely useful in monitoring velocities in the intracranial ICA and MCA, where mean maximum velocities of ≥ cm/s are associated with an increased risk of ischemic stroke. ,

This manual was developed by the ACR Committee on Drugs and Contrast Media of the ACR Commission on Quality and Safety as a guide for radiologists to enhance the safe and effective use of contrast media. This manual was developed by the ACR Committee on Drugs and Contrast Media of the ACR Com- mission on General, Small and/or Rural Radiology as a guide for radiologists to enhance the safe and effective use of contrast media. ACR Manual on Contrast Media – Version 8, Preface / 3 Preface This Eighth Edition of the ACR Manual on Contrast Media replaces all earlier editions. It is be-ing published as a Web-based document only so it can be updated as frequently as needed. This manual was developed by the ACR Committee on Drugs and Contrast Media of the ACR.